NFAT2 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-93184-60, E-AB-93184-120, E-AB-93184-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: NFAT2
Target Synonym: NF-ATC; NF-ATc1.2; NFAT2; NFATc; NFATC1
Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: WB, IHC
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: O95644
Background: The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human NFAT2
Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:200
Calculated MW: 38kDa/74- 88kDa/100-101kDa
Observed MW: 75-100kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only