NFKBID Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-13857-60, E-AB-13857-120, E-AB-13857-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: NFKBID
Target Synonym: I-kappa-B-delta; IkappaBdelta; IkappaBNS; IkB-delta; IKBD; IKBNS; NF-kappa-B inhibitor delta; NFKBID; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor delta; T-cell activation NFKB-like protein; TA-NFKBH
Research Areas: Epigenetics and Nuclear Signaling, Immunology, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: WB, IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q8NI38
Background: May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IκBNS, the nuclear IκB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. IκBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.
Concentration: 0.4 mg/mL
Immunogen: Recombinant protein of human NFKBID
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:200-1:1000, IHC 1:25-1:100
Calculated MW: 33kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only