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NFKBIZ Polyclonal Antibody - E-AB-68265

NFKBIZ Polyclonal Antibody - E-AB-68265

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NFKBIZ Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-68265-60, E-AB-68265-120, E-AB-68265-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NFKBIZ

Target Synonym: NFKBIZ; IKBZ; INAP; MAIL

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Immunology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9BYH8

Background: This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human NFKBIZ

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 64kDa/68kDa/78kDa

Observed MW: 64KDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only