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NLRP1 Polyclonal Antibody - E-AB-93147

NLRP1 Polyclonal Antibody - E-AB-93147

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NLRP1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-93147-60, E-AB-93147-120, E-AB-93147-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NLRP1

Target Synonym: NLRP1; AIADK; CARD7; CIDED; CLR17.1; DEFCAP; DEFCAP-L/S; MSPC; NAC; NALP1; PP1044; SLEV1; VAMAS1

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9C000

Background: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human NLRP1

Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200, IF 1:50-1:200

Calculated MW: 46kDa/83kDa/154-165kDa

Observed MW: 160KDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

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