NLRP6 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-13438-60, E-AB-13438-120, E-AB-13438-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: NLRP6
Target Synonym: Angiotensin II/vasopressin receptor; AVR; CLR11.4; NACHT; leucine rich repeat and PYD containing 6; NACHT; LRR and PYD containing protein 6; NACHT; LRR and PYD domains-containing protein 6; NAVR; NAVR/AVR; NLR family; pyrin domain containing 6; Nlrp6; NLRP6; Nucleotide binding oligomerization domain; leucine rich repeat and pyrin domain containing 6; PAN3; PYPAF5; PYRIN containing APAF1 like protein 5; PYRIN-containing APAF1-like protein 5
Research Areas: Cell Biology, Immunology, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P59044
Background: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.
Concentration: 0.3 mg/mL
Immunogen: Synthetic peptide of human NLRP6
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only