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NLRP7 Polyclonal Antibody - E-AB-13071

NLRP7 Polyclonal Antibody - E-AB-13071

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NLRP7 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-13071-60, E-AB-13071-120, E-AB-13071-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NLRP7

Target Synonym: CLR19.4; FLJ94610; HYDM; MGC126470; MGC126471; NACHT; leucine rich repeat and PYD containing 7; NACHT; LRR and PYD containing protein 7; NACHT; LRR and PYD domains containing protein 7; NACHT; LRR and PYD domains-containing protein 7; NALP7; NALP7; NLR family; pyrin domain containing 7; NLRP7; NOD12; Nucleotide-binding oligomerization domain protein 12; Nucleotide-binding oligomerization domain; leucine rich repeat and pyrin domain containing 7; PAN7; PYPAF3; PYRIN-containing APAF1-like protein 3

Research Areas: Cell Biology, Immunology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q8WX94

Background: This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration: 0.3 mg/mL

Immunogen: Synthetic peptide of human NLRP7

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only