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NME1 Polyclonal Antibody - E-AB-14249

NME1 Polyclonal Antibody - E-AB-14249

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NME1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-14249-60, E-AB-14249-120, E-AB-14249-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NME1

Target Synonym: AWD; AWD; drosophila; homolog of; GAAD; Granzyme A activated DNase; Granzyme A-activated DNase; GZMA activated DNase; Metastasis inhibition factor NM23; NB; NBS; NDK A; NDKA; NDKA; NDP kinase A; NDPK-A; NDPKA; NM23; NM23 long variant; included; nm23-H1; NM23-M1; NM23H1B; included; NME/NM23 nucleoside diphosphate kinase 1; Nme1; NME1-NME2 spliced read-through transcript; included; Non-metastatic cells 1; protein (NM23A) expressed in; Nonmetastatic cells 1; protein expressed in; Nonmetastatic protein 23; Nonmetastatic protein 23; homolog 1; Nucleoside diphosphate kinase A; Tumor metastatic process-associated protein

Research Areas: Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P15531

Background: This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Concentration: 0.4 mg/mL

Immunogen: Recombinant protein of human NME1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Calculated MW: 17kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only