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NPHP3 Polyclonal Antibody - E-AB-92891

NPHP3 Polyclonal Antibody - E-AB-92891

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NPHP3 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-92891-60, E-AB-92891-120, E-AB-92891-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NPHP3

Target Synonym: NPHP3; CFAP31; MKS7; NPH3; RHPD; RHPD1; SLSN3

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q7Z494

Background: This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin, it is required for normal ciliary development, and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3, and also with renal-hepatic-pancreatic dysplasia, and Meckel syndrome type 7. Naturally occurring read-through transcripts exist between this gene and the downstream ACAD11 (acyl-CoA dehydrogenase family, member 11) gene.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human NPHP3

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:200-1:2000

Calculated MW: 15kDa/19kDa/26kDa/71kDa/73kDa/79kDa/150kDa

Observed MW: 151kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only