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NRF2 Polyclonal Antibody - E-AB-68254

NRF2 Polyclonal Antibody - E-AB-68254

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NRF2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-68254-60, E-AB-68254-120, E-AB-68254-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NRF2

Target Synonym: NFE2L2; HEBP1; NRF2

Research Areas: Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q16236

Background: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human NRF2

Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Calculated MW: 65kDa/66kDa/67kDa

Observed MW: 97-100KDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only