OCT4 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-68415-60, E-AB-68415-120, E-AB-68415-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: 45569
Target Synonym: POU5F1; OCT3; OCT4; OTF-3; OTF3; OTF4; Oct-3; Oct-4
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: WB, IHC
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q01860
Background: This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
Concentration: 1 mg/mL
Immunogen: A synthetic peptide of human OCT4
Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:200
Calculated MW: 30kDa/38kDa
Observed MW: 45KDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only