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PAK1IP1 Polyclonal Antibody - E-AB-91881

PAK1IP1 Polyclonal Antibody - E-AB-91881

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PAK1IP1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-91881-60, E-AB-91881-120, E-AB-91881-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: PAK1IP1

Target Synonym: MAK11; PIP1; WDR84; bA421M1.5; hPIP1; PAK1IP1

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9NWT1

Background: Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human PAK1IP1

Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 43kDa

Observed MW: 44kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only