PE/Cyanine5.5 Anti-Mouse CD45 Antibody [30-F11] - E-AB-F1136UI

PE/Cyanine5.5 Anti-Mouse CD45 Antibody [30-F11]

Size: 100μg

Catalogue Number: E-AB-F1136UI-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD45

Target Synonym: Receptor-type tyrosine-protein phosphatase C, Ptprc, L-CA, Ly-5, T200, CD45,

Conjugation: PE/Cyanine5.5

Host: Rat

Species Reactivity: Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Isotype: Rat IgG2b, κ

Clone No.: 30-F11

UNIProt ID: P06800

Background: CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Concentration: 0.2 mg/mL

Control Catalogue Number: E-AB-F09843I

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 19264

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag