PerCP Anti-Human CD40 Antibody [3A8] - E-AB-F1037F

PerCP Anti-Human CD40 Antibody [3A8]

Sizes: 100 Tests, 100 Tests×2

Catalogue Numbers: E-AB-F1037F-100, E-AB-F1037F-100×2

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD40

Target Synonym: Tumor necrosis factor receptor superfamily member 5, Cd40, B-cell surface antigen CD40, Bp50, CD40L receptor, CD40, Tnfrsf5,

Conjugation: PerCP

Host: Mouse

Species Reactivity: Human

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Isotype: Mouse IgG2a, κ

Clone No.: 3A8

UNIProt ID: P25942

Background: CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.

Concentration: 5 μL/Test

Control Catalogue Number: E-AB-F09802F

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Gene ID: 958

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag

Research Use Only