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Phospho-ERK 1/2 (Thr202/Tyr204) Polyclonal Antibody - E-AB-70310

Phospho-ERK 1/2 (Thr202/Tyr204) Polyclonal Antibody - E-AB-70310

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Phospho-ERK 1/2 (Thr202/Tyr204) Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-70310-60, E-AB-70310-120, E-AB-70310-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: ERK1/2

Target Synonym: MAPK3; ERK1; PRKM3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase

Research Areas: Cancer, Neuroscience, Signal Transduction, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P63085,Q63844

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

Concentration: 1.1 mg/mL

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse ERK2

Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 42/44kDa

Observed MW: 42/44kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

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