Phospho-IRS1 (Tyr896) Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-21407-60, E-AB-21407-120, E-AB-21407-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: IRS-1 (phospho Tyr896)
Target Synonym: HIRS 1; HIRS1; Insulin receptor substrate 1; IRS 1; IRS-1; IRS1; IRS1; OTTHUMP00000164234
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction, Tags and Cell Markers
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P35568
Background: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.
Concentration: 1 mg/mL
Immunogen: Synthesized peptide derived from human IRS-1 around the phosphorylation site of Tyr896
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, ELISA 1:40000
Calculated MW: 132kDa
Observed MW: 180kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only