PON3/paraoxonase 3 Polyclonal Antibody
Sizes: 50μL, 100μL, 200μL
Catalogue Numbers: E-AB-40576-50, E-AB-40576-100, E-AB-40576-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: PON3
Target Synonym: Serum paraoxonase/lactonase 3; PON3
Research Areas: Neuroscience,Cardiovascular,Signal Transduction,Metabolism
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Mouse, Rat
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q15166
Background: The paraoxonase (PON) gene family of antioxidant enzymes includes three known members located adjacent to each other on chromosome 7. Paraoxonase/lactonase 3 (PON3) is a 354 amino acid, 39.6 kDa protein that is secreted into the bloodstream and associates with high-density lipoprotein (HDL). PON3 has lactonase activity (EC 3.1.1) and rapidly hydrolyzes lactones. PON3 exhibits no paraoxonase and very limited arylesterase activities. PON3 is an important antioxidant and can inhibit the oxidation of low-density lipoprotein (LDL), a function that may slow the initiation and progression of atherosclerosis.
Concentration: 2mg/mL
Immunogen: Recombinant Human PON3 protein expressed by E.coli.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Purification Method: Antigen Affinity Purification
Dilution: WB: 1:1000-2000
Calculated MW: 39kDa
Observed MW: 40kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only