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PPM1K Polyclonal Antibody - E-AB-53177

PPM1K Polyclonal Antibody - E-AB-53177

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PPM1K Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53177-60, E-AB-53177-120, E-AB-53177-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: PPM1K

Target Synonym: BDP; mitochondrial; MSUDMV; PP2C domain containing protein phosphatase 1K; PP2C domain-containing protein phosphatase 1K; PP2C kappa; PP2C like mitochondrial protein; PP2C type mitochondrial phosphoprotein phosphatase; PP2C-kappa; PP2C-like mitochondrial protein; PP2C-type mitochondrial phosphoprotein phosphatase; PP2Ckappa; PP2CM; PPM1K; PPM1K; Protein phosphatase 1K; Protein phosphatase 1K; mitochondrial; Protein phosphatase 2C isoform kappa; Protein phosphatase Mg2+/Mn2+ dependent 1K; PTMP; UG0882E07

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction, Tags and Cell Markers

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q8N3J5

Background: This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore.PPM1K (Protein Phosphatase, Mg2+/Mn2+ Dependent 1K) is a Protein Coding gene. Diseases associated with PPM1K include Maple Syrup Urine Disease, Mild Variant and Intermediate Maple Syrup Urine Disease. Among its related pathways are Valine, leucine and isoleucine degradation and Viral mRNA Translation. GO annotations related to this gene include protein serine/threonine phosphatase activity. An important paralog of this gene is PPM1E.

Concentration: 0.78 mg/mL

Immunogen: Fusion protein of human PPM1K

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:100, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only