PRPF8 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-62352-60, E-AB-62352-120, E-AB-62352-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: PRPF8
Target Synonym: PRPF8; HPRP8; PRP8; PRPC8; RP13; SNRNP220; PRPF8
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC, IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q6P2Q9
Background: Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human PRPF8 (NP_006436.3).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100
Calculated MW: 273kDa
Observed MW: 274kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only