PTPN22 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-60305-60, E-AB-60305-120, E-AB-60305-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: PTPN22
Target Synonym: PTPN22; LYP; LYP1; LYP2; PEP; PTPN22.5; PTPN22.6; PTPN8
Research Areas: Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9Y2R2
Background: This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human PTPN22 (NP_036543.4).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: IF 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only