PTPRN Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-52202-60, E-AB-52202-120, E-AB-52202-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: PTPRN
Target Synonym: CA 512; FLJ16131; IA 2; IA 2/PTP; IA2; IA2/PTP; ICA 3; ICA 512; ICA3; ICA512; Islet cell antigen 2; Islet cell antigen 512; Islet cell autoantigen 3; Protein tyrosine phosphatase like N; Protein tyrosine phosphatase like N precursor; Protein tyrosine phosphatase receptor type N; PTP IA 2; PTP IA-2; PTP IA2; PTPIA 2; PTPN; Ptprn; PTPRN protein; PTPRN; R PTP N; R-PTP-N; Receptor type tyrosine protein phosphatase like N; Receptor-type tyrosine-protein phosphatase-like N; RPTPN
Research Areas: Cancer, Metabolism, Neuroscience, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q16849
Background: IA-2/PTPRN is a member of the protein tyrosine phosphatase (PTP) family, which contains a transmembrane region, an intracellular PTP-like domain and an extracellular N-terminus. Experiments found that IA-2/PTPRN localizes to secretory granules and is exclusively expressed in neuroendocrine cells (including pancreatic islets cell). IA-2/PTPRNwas found to be a major autoantigen in insulin-dependent diabetes mellitus and the detection of autoantibodies against IA-2/PTPRN is commonly used as a diabetes diagnosis marker.
Concentration: 0.96 mg/mL
Immunogen: Fusion protein of human PTPRN
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only