pum1 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-64604-60, E-AB-64604-120, E-AB-64604-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: pum1
Target Synonym: PUM1; HSPUM; PUMH; PUMH1; PUML1
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q14671
Background: This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human pum1 (NP_055491.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: IF 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only