Purified Anti-Human CD58 Antibody [TS2/9.1]
Size: 100μg
Catalogue Number: E-AB-F1068A-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: CD58
Target Synonym: Lymphocyte function-associated antigen 3, CD58, Ag3, Surface glycoprotein LFA-3, LFA3,
Conjugation: Unconjugated
Host: Mouse
Species Reactivity: Human
Application: FCM
Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Isotype: Mouse IgG1, κ
Clone No.: TS2/9.1
UNIProt ID: P19256
Background: CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface.
Concentration: 0.5 mg/mL
Control Catalogue Number: E-AB-F09793A
Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
GeneID: 965
Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.
Shipping: Ice bag