Purified Anti-Human CD86 Antibody [BU63] - E-AB-F1012A

Purified Anti-Human CD86 Antibody [BU63]

Size: 100μg

Catalogue Number: E-AB-F1012A-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD86

Target Synonym: T-lymphocyte activation antigen CD86, Cd86, Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1,

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: Human

Application: FCM, Block

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Mouse IgG1, κ

Clone No.: BU63

UNIProt ID: P42081

Background: CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F09793A

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.

GeneID: 942

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag