RAB3IP Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-63202-60, E-AB-63202-120, E-AB-63202-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: RAB3IP
Target Synonym: RAB3IP; RABIN3; RABIN8
Research Areas: Cell Biology,Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q96QF0
Background: Guanine nucleotide exchange factor (GEF which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS, apical surface formation and lumenogenesis.
Concentration: 1 mg/mL
Immunogen: Recombinant fusion protein of human RAB3IP
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 28kDa/33-53kDa
Observed MW: 53kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only