RAP1A Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-13927-60, E-AB-13927-120, E-AB-13927-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: RAP1A
Target Synonym: C21KG; G-22K; GTP-binding protein smg p21A; KREV1; RAP1A; RAP1A; member of RAS oncogene family; RAP1A; Ras-related protein 1A; Ras-related protein Krev-1; Ras-related protein Rap-1A; SMGP21
Research Areas: Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P62834
Background: The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.
Concentration: 0.3 mg/mL
Immunogen: Recombinant protein of human RAP1A
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only