RARB Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-66657-60, E-AB-66657-120, E-AB-66657-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: RARB
Target Synonym: RARB; HAP; MCOPS12; NR1B2; RARbeta1; RRB2
Research Areas: Cancer,Epigenetics and Nuclear Signaling,Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Rat
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P10826
Background: This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants.
Concentration: 1 mg/mL
Immunogen: A synthetic peptide of human RARB
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 37kDa/50kDa
Observed MW: 60kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only