Recombinant chiken IGF1/IGF‑I/IGF-1 protein (His tag)
Size: 100μg
Catalogue Numbers: PDEO100008-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: IGF1; IGF-1
Target Synonym: Insulin-like growth factor I; IGF1;
UNIProt ID: P18254
Research Areas: Cancer; Developmental Biology; Neuroscience; signal Transduction; Stem Cells; Metabolism
Target Species: Chicken
Expression Host: E.coli
Fusion Tag: N-His
Accession: P18254
Background: Insulin-like growth factor I (IGF-I or IGF-1), also known as somatomedin C, is the dominant effector of growth hormone and is structurally homologous to proinsulin. IGF-I induces the proliferation, migration, and differentiation of a wide variety of cell types during development and postnatally. IGF-I regulates glucose and fatty acid metabolism, steroid hormone activity, and cartilage and bone metabolism. It plays an important role in muscle regeneration and tumor progression. IGF-I/IGF-1 binds IGF-I R, IGF-II R, and the insulin receptor, although its effects are mediated primarily by IGF-I R. The IGF-I protein associates with IGF binding proteins thereby increasing its plasma half-life and modulating its interactions with receptors.
Sequence: Gly 49-Met 153
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 11.44 kDa
Observed MW: 13 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only