Recombinant Cynomolgus Thymic Stromal Lymphopoietin/TSLP (C-6His)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSQ050102-10, PKSQ050102-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: TSLP
Target Symptom: Thymic stromal lymphopoietin; Thymic stroma-derived lymphopoietin; TSLP
Target Species: Cynomolgus macaques
Expression Host: E.coli
Application: ELISA
Fusion Tag: C-6His
Accession: XP_005557555.1
Background: Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. TSLP induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. It can induce allergic inflammation by directly activating mast cells. TSLP is produced mainly by non-hematopoietic cells such as fibroblasts, epithelial cells and different types of stromal or stromal-like cells. These cells are located in regions where TSLP activity is required.
Activity: Immobilized Mouse TSLPR-Fc(Cat#PKSM041158) at 10μg/ml (100 μl/well) can bind Biotinylated Cynomolgus TSLP-His(Cat#PKSQ050102). The ED50 of Cynomolgus TSLP-His(Cat#PKSQ050102)is 3. 2ug/ml.
Sequence: Tyr29-Gln159(Glu37Gln)
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 16.2 kDa
Observed MW: 16 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only