Recombinant Cytochrome P450 2D6 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81500-50, E-AB-81500-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: Cytochrome P450 2D6
Target Synonym: CPD6; CYP2D; CYP2D6; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; CYP2DL1; CYPIID6; Cytochrome P450 DB1; Cytochrome P450 family 2 subfamily D member 6; Cytochrome P450 family 2 subfamily D polypeptide 6; Debrisoquine 4 hydroxylase; Flavoprotein linked monooxygenase; Microsomal monooxygenase; P450 DB1; P450C2D; P450DB1; Xenobiotic monooxygenase
Research Areas: Cardiovascular, Metabolism, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: WB, IHC-P, IF
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R07-3G8
UNIProt ID: P10635
Background: CYP2D6(Cytochrome P450 2D6) is also named as CYP2DL1 and belongs to the cytochrome P450 family. It is a monooxygenase that involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants. CYP2D6 is responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It has 2 isoforms produced by alternative splicing with the molecular weight of 56 kDa and 50 kDa.
Concentration: 300 μg/mL
Immunogen: Recombinant protein of human CYP2D6
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:500-1:1000 IHC 1:50-1:100 IF 1:50-1:100
Calculated MW: 56kDa
Observed MW: 50kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only