Recombinant ERK2 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81446-50, E-AB-81446-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: ERK2
Target Synonym: ERK 2; ERK; ERK-2; ERT1; Extracellular Signal Regulated Kinase 2; Extracellular signal-regulated kinase 2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; MAPK 1; MAPK 2; Mapk1; MAPK2; Mitogen-activated protein kinase 1; Mitogen-activated protein kinase 2; MK01; P38; P40; P41; p42-MAPK; P42MAPK; PRKM1; PRKM2; protein kinase; mitogen-activated; 1; protein kinase; mitogen-activated; 2; protein tyrosine kinase ERK2
Research Areas: Cancer, Neuroscience, Signal Transduction, Stem Cells
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC-P
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R07-1A9
UNIProt ID: P28482
Background: This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Concentration: 300 μg/mL
Immunogen: A synthetic peptide of human ERK2
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:500-1:1000 IHC 1:20-1:100 IF 1:50-1:100
Calculated MW: 41kDa
Observed MW: 41kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only