Recombinant Human ALDH1A1/ALDC Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032052-10, PKSH032052-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: ALDH1A1; ALDC
Target Synonym: Retinal Dehydrogenase 1; RALDH 1; RalDH1; ALDH-E1; ALHDII; Aldehyde Dehydrogenase Family 1 Member A1; Aldehyde Dehydrogenase Cytosolic; ALDH1A1; ALDC; ALDH1; PUMB10; ALDH11; HEL-9; HEL-S-53e; HEL12; PUMB1; RALDH1
UNIProt ID: P00352
Research Areas: Neuroscience; Cancer; Stem cells
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-6His
Accession: P00352
Background: Aldehyde Dehydrogenase Family 1 Member A1 (ALDH1A1) is a cytoplasmic enzyme that belongs to the Aldehyde Dehydrogenase family. ALDH1A1 is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties and subcellular localizations. ALDH1A1 is the main cytosolic isoform, which has a lower affinity for aldehydes than the mitochondrial enzyme. ALDH1A1 binds free retinal and cellular retinol-binding protein-bound retinal. It can convert/oxidize retinaldehyde to retinoic acid.
Sequence: Met 1-Ser501
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH8.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 57.0 kDa
Observed MW: 60 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only