Recombinant Human ALDH1A3 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033774-10, PKSH033774-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: ALDH1A3
Target Symptom: Aldehyde dehydrogenase family 1 member A3; ALDH1A3; Aldehyde dehydrogenase 6; Retinaldehyde dehydrogenase 3; RALDH-3; ALDH6; ALDH1A6; MCOP8; RALDH3
Research Area: Signal Transduction; Neuroscience; metabolism;
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: P47895
Accession: P47895
Background: Aldehyde dehydrogenase 1 family member A3 (ALDH1A3), also known as retinaldehyde dehydrogenase 3 (RALDH3), is a member of the aldehyde dehydrogenase family known to metabolize a wide variety of aldehydes. ALDH1A3 specifically oxidizes retinal to retinoic acid (RA) and is differentially expressed in developing embryonic tissues and adult organs. The RA produced by ALDH1A3 in rodents contributes to the development of skin and hair follicles, brain, tooth buds, lungs, olfactory bulbs, kidneys, eyes, skeletal muscle and seminal vesicles. In recent research, ALDH1A3 could be as a marker of cancer stem cell to predict metastasis or clinical prognosis in many cancers.
Sequence: Met1-Pro512
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mMNaCl, pH7.5, 20% Glycerol.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 57.5 kDa
Observed MW: 55-60 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only