Recombinant Human AMIGO2 Protein (aa 40-393, His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033769-10, PKSH033769-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: AMIGO2
Target Symptom: Amphoterin-Induced Protein 2; AMIGO-2; Alivin-1; Differentially Expressed in Gastric Adenocarcinomas; DEGA; ALI1
Research Area: Neuroscience
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-His
UNIProt ID: Q86SJ2
Accession: Q86SJ2
Background: Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain; 6 LRR (leucine-rich) repeats; a LRRCT domain; as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast; ovary; cervix; and uterus; although lower in lung; colon; and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO2 may contribute to signal transduction through its intracellular domain; and may be required for tumorigenesis of a subset of gastric adenocarcinomas.
Sequence: Val40-His393
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 41.34 kDa
Observed MW: 68 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only