Recombinant Human ANXA5/Annexin Ⅴ/Annexin A5 Protein
Sizes: 20μg, 100μg
Catalogue Numbers: PKSH031601-20, PKSH031601-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: ANXA5; Annexin Ⅴ; Annexin A5
Target Synonym: ANXA5; Annexin V; Unconjugated Annexin V; Annexin-5; Anchorin CII; Calphobindin I; Endonexin II; Lipocortin V; Placental anticoagulant protein 4; Placental anticoagulant protein I; Thromboplastin inhibitor; Vascular anticoagulant-alpha
UNIProt ID: P08758
Research Areas: Cell biology; Cardiovascular; Cancer
Target Species: Human
Expression Host: E.coli
Fusion Tag: None
Accession: P08758
Background: Peptidyl-prolyl cis-trans isomerase A; also known as PPIase A; Rotamase A; Cyclophilin A; Cyclosporin A-binding protein; PPIA and CYPA; is a cytoplasm protein which belongs to thecyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins (CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity; suggesting that they influence the conformation of proteins in cells. PPIA / Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA / Cyclophilin A is secreted by vascular smooth muscle cells in response to inflammatory stimuli; and could thus contribute to atherosclerosis. It is not essential for mammalian cell viability. PPIA / Cyclophilin A can interact with several HIV proteins; including p55 gag; Vpr; and capsid protein; and has been shown to be necessary for the formation of infectious HIV virions.
Sequence: Met 1-Asp 320
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile 50mM Tris, 240mM NaCl, pH 8.5
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 35.9 kDa
Observed MW: 34 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only