Recombinant Human ATXN7L1 protein (His tag)
Size: 100μg
Catalogue Number: PDEH100313-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: ATXN7L1
Target Symptom: Ataxin-7-like protein 1; ATXN7L1; Ataxin-7-like protein 1; Ataxin-7-like protein 4
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His & C-His
UNIProt ID: Q9ULK2
Accession: Q9ULK2-2
Background: ATXN7 is found in the cytoplasm of all the populations of neurons analyzed in control brains, but nuclear labeling is observed in some neurons with a frequency and intensity weakly correlated with the topography of lesions in patients. Ataxin-7 is a component of the Tata binding protein (TBP)-free TAF-containing complex (TFTC) and the SPT3/TAF9/GCN5 acetyltransferase complex (STAGA), which is implicated in several steps of transcriptional regulation such as histone acetylation/deubiquitinylation and recruitment of the preinitiation complex to promoters.
Sequence: Met 1- Ala 146
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 15.95 kDa
Observed MW: 20 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only