Recombinant Human BLVRA Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032118-10, PKSH032118-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: BLVRA
Target Synonym: BLVRA; Biliverdin reductase A; BVR A; Biliverdin-IX alpha-reductase; BLVR; BVR
UNIProt ID: P53004
Research Areas: Signal Transduction; Cell biology; metabolism;
Target Species: Human
Expression Host: E.coli
Fusion Tag: C-6His
Accession: P53004
Background: Human Biliverdin reductase A (BLVRA) is belonged to the Gfo/Idh/MocA family and Biliverdin reductase subfamily. BLVRA is an enzyme that in humans is encoded by the BLVRA gene. BLVRA plays an important role in reducing the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. BLVRA acts on biliverdin by reducing its double-bond between the pyrrole rings into a single-bond. It accomplishes this using NADPH + H+ as an electron donor, forming bilirubin and NADP+ as products.
Sequence: Glu6-Ser294
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, 0.05% Brij35, 20%Glycerol, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 33.8 kDa
Observed MW: 40 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only