Recombinant Human Cadherin-11/CDH11 Protein (Fc & His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032137-10, PKSH032137-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: Cadherin-11; CDH11
Target Synonym: Cadherin 11 Type 2 OB-cadherin (Osteoblast); Cadherin 11 Type 2 OB-Cadherin (Osteoblast) Isoform CRA_c; CDH11
UNIProt ID: Q96CZ9
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-Fc-6His
Accession: Q96CZ9
Background: Cadherin-11; also known as OSF-4; Osteoblast cadherin and CDH11; is a type II classical cadherin from the cadherin superfamily; integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells; may thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in brain. Mature cadherin proteins consists of a large N-terminal extracellular domain; a single membrane-spanning domain; and a small; highly conserved C-terminal cytoplasmic domain. It is shown that cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.
Sequence: Phe23-Thr617
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 93.5 kDa
Observed MW: 110 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only