Recombinant Human Cathepsin A/CTSA Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032178-10, PKSH032178-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: Cathepsin A; CTSA
Target Synonym: Lysosomal protective protein; CTSA; Carboxypeptidase C; Carboxypeptidase L; Cathepsin A; GLB2; GSL; NGBE; PPCA; PPGB
UNIProt ID: P10619
Research Areas: Signal Transduction; metabolism;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: P10619
Background: Cathepsin A is active in cellular compartments called lysosomes. These compartments contain enzymes that digest and recycle materials when they are no longer needed. Cathepsin A interacts with the enzymes β-galactosidase and neuraminidase 1, which play a role in the breakdown of complexes of sugar molecules (oligosaccharides) attached to certain proteins (glycoproteins) or fats (glycolipids). Cathepsin A forms a complex with these two enzymes and directs their transport within the cell to the lysosomes. Within lysosomes, cathepsin A activates the enzymes and prevents their breakdown.
Sequence: Ala29-Tyr480
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 52.2 kDa
Observed MW: 58-60 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only