Recombinant Human Cathepsin L/CTSL Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032182-10, PKSH032182-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: Cathepsin L; CTSL
Target Synonym: Cathepsin L1; Major Excreted Protein; MEP; CTSL1; CTSL
UNIProt ID: P07711
Research Areas: Signal Transduction; Neuroscience;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: P07711
Background: Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation. Unlike the precursor forms of other papain family members, the 43 kDa pro-cathepsin L itself is secreted from various cells. Pro-cathepsin L is the major excreted protein of malignantly transformed mouse fibroblasts and is also one of the major acidic cysteine proteases in mammalian cells.
Sequence: Thr18-Val333
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 4.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 36.9 kDa
Observed MW: 34 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only