Recombinant Human Cathepsin L2/CTSL2 Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032183-10, PKSH032183-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: Cathepsin L2; CTSL2
Target Synonym: Cathepsin L2; Cathepsin U; Cathepsin V; CTSL2; CATL2; CTSU; CTSV
UNIProt ID: O60911
Research Areas: Signal Transduction;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: O60911
Background: Cathepsin L2 belongs to the Peptidase C1 family. Cathepsin L2 can be autocatalytically convertedto the mature form as a proenzyme in lysosomes at pH=7.0. Cathepsin L2 cannot be expressed in normal mammary gland, colon and peritumoral tissue, but it can be expressed in breast carcinomas and colorectal tissues. These suggeats Cathepsin L2 may play a role in tumor processes. Cathepsin L2 is specifically expressed in the testis, thymus, and corneal epithelium.
Sequence: Val18-Val334
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 36.7 kDa
Observed MW: 39 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only