Recombinant Human CCL1/I-309 Protein
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033809-10, PKSH033809-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: CCL1; I-309
Target Symptom: C-C Motif Chemokine 1; Small-Inducible Cytokine A1; T Lymphocyte-Secreted Protein I-309;
CCL1; SCYA1
Research Area: immunology
Target Species: Human
Expression Host: E.coli
Fusion Tag: None
UNIProt ID: P22362
Accession: P22362
Background: Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a
central role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a
homologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequence
identity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines.
CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface
chemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell
fusion and virus infection.
Sequence: Lys24-Lys96
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 8.62 kDa
Observed MW: 10 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only