Recombinant Human CEACAM5/CEA Protein (Fc Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032237-10, PKSH032237-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: CEACAM5; CEA
Target Synonym: Carcinoembryonic antigen-related cell adhesion molecule 5; CEACAM5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e
UNIProt ID: P06731
Research Areas: Tags & Cell Markers; Microbiology; Cancer; immunology; Stem cells
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-Fc
Accession: P06731
Background: Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell–cell recognition. CEACAM5; also called CEA and CD66e; is characterized by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells; and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas; and its overexpression can protect tumor cells from apoptosis. It is commonly used as a cancer marker.
Sequence: Lys35-Ala685
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 98.9 kDa
Observed MW: 155-180 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only