Recombinant Human CEACAM8/CD66b Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH032239-10, PKSH032239-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: CEACAM8; CD66b
Target Synonym: Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8; CD67 Antigen; Carcinoembryonic Antigen CGM6; Non-Specific Cross-Reacting Antigen NCA-95; CD66b; CEACAM8; CGM6
UNIProt ID: P31997
Research Areas: immunology
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
Accession: P31997
Background: Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8) is a single chain, GPI-anchored, highly glycosylated protein which belongs to the immunoglobulin superfamily and the carcinoembryonic antigen(CEA) family. CEACAM8 is expressed by neutrophils and eosinophils, and serves as a binding partner for CEACAM-6 and Galectin-3. It contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. Mature human CEACAM8 is a 287 amino acid GPI-linked glycoprotein. CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migration, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells.
Sequence: Gln35-His141
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 13.0 kDa
Observed MW: 17-19 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only