Recombinant Human DRP1 protein (His tag)
Size: 100μg
Catalogue Numbers: PDEH100411-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: DRP1
Target Synonym: Dynamin-1-like protein; DNM1L; Dnm1p/Vps1p-like protein (DVLP); Dynamin family member proline-rich carboxyl-terminal domain less (Dymple); Dynamin-like protein
UNIProt ID: O00429
Research Areas: Cancer;
cell Biology;
Metabolism; Neuroscience; signal Transduction
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-His
Accession: O00429
Background: Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into ring-like structures which wrap around the scission site to constict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Required for normal brain development. Facilitates developmentally-regulated apoptosis during neural tube development. Required for a normal rate of cytochrome c release and caspase activation during apoptosis. Also required for mitochondrial fission during mitosis. May be involved in vesicle transport.
Sequence: Asn 448-Trp 736
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 30.58 kDa
Observed MW: 35 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only