Recombinant Human Ephrin-A5/EFNA5 protein (His tag)
Sizes: 20μg, 100μg
Catalogue Numbers: PDMH100084-20, PDMH100084-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: Ephrin-A5; EFNA5
Target Synonym: Ephrin-A5; EPLG7; LERK7; EFNA5; LERK-7; EPH-related receptor tyrosine kinase ligand 7; AL-1
UNIProt ID: P52803
Research Areas: Signal Transduction; Neuroscience;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-His
Accession: P52803
Background: Ephrin-A5 (EFNA5) belongs to the ephrin family, contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-A5 is a cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.
Sequence: Met1-Asn203
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: Please contact us for more information.
Calculated MW: 32.67 kDa
Observed MW: 32 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only