Recombinant Human FGL1 (C-Avi-6His) Biotinylated
Sizes: 20μg, 100μg
Catalogue Numbers: PKSH033856-20, PKSH033856-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: FGL1
Target Symptom: Fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1
Research Area: Cardiovascular
Conjugation: Biotinylated
Target Species: Human
Expression Host: HEK293 Cells
Application: ELISA
Fusion Tag: C-Avi-6His
UNIProt ID: Q08830
Accession: Q08830
Background: Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.
Activity: Immobilized Human LAG-3-Fc at 10μg/ml (100 μl/well) can bind Biotinylated Human FGL1-Avi. The ED50 of Human FGL1-Avi is 1908ng/mL.
Sequence: Leu23-Ile312
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 300mM NaCl, 10% Glycerol, 2mM EDTA, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 36.6 kDa
Observed MW: 35 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only