Recombinant Human Follistatin 288/FST Protein
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033674-10, PKSH033674-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: Follistatin 288; FST
Target Symptom: follistatin isoform FST317; Follistatin; FS; FSActivin-binding protein; FST
Research Area: Signal Transduction; epigenetics and nuclear signal;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
UNIProt ID: P19883
Accession: P19883
Background: Follistatin 288 is a secreted glycoprotein that was first identified as a follicle-stimulating hormone inhibiting substance in ovarian follicular fluid. Human follistatin 288 cDNA encodes a 317 amino acid (aa) protein with a 29aa signal sequence, and a 288 aa mature region.Follistatin shows the highest affinity for activins due to its extended configuration. Genetic deletion of follistatin in mice, or expression of only the Follistatin form, is perinatally lethal due to defects of lung, skin and musculoskeletal system. Follistatins also regulate hematopoietic stem cell adhesion to fibronectin via FS2.
Sequence: Gly30-Asn317
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 32.4 kDa
Observed MW: 33-42 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only