Recombinant Human GGCT Protein (His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033273-10, PKSH033273-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: GGCT
Target Symptom: Gamma-Glutamylcyclotransferase; Cytochrome C-Releasing Factor 21; GGCT; C7orf24; CRF21
Research Area: Cell biology; Cancer; metabolism
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-6His
UNIProt ID: O75223
Accession: O75223
Background: Human Υ-Glutamylcyclotransferase belongs to the Transferases family, specifically the Aminoacyltransferase. Gamma-Glutamylcyclotransferase catalyzes the formation of 5-Pxoproline from Gamma-Glutamyl Dipeptides. It plays an important role in Glutathione Homeostasis. Gamma-Glutamylcyclotransferase induces the release of Cytochrome C from the mitochondria resulting in the induction of apoptosis.
Sequence: Met 1-Leu188
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 23.2 kDa
Observed MW: 23 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only