Recombinant Human GMPR Protein (Human Cells, His Tag)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH033290-10, PKSH033290-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: GMPR
Target Symptom: GMP Reductase 1; Guanosine 5'-Monophosphate Oxidoreductase 1; Guanosine Monophosphate Reductase 1; GMPR; GMPR1
Research Area: Signal Transduction; Cell biology;
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-6His
UNIProt ID: P36959
Accession: P36959
Background: GMP Reductase 1 (GMPR) is a member of the IMPDH/GMPR family. GMPR exists as a homotetramer and catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase; nucleoside and nucleotide derivatives of G to A nucleotides; and in maintaining the intracellular balance of A and G nucleotides. GMP reductase gene expression may be regulated by MITF. At least two different alleles are known.
Sequence: Met 1-Ser345
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 40% glycerol, 0.15M NaCl and 1mM DTT, pH8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Not Applicable
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 38.5 kDa
Observed MW: 38.5 kDa
Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Research Use Only