Recombinant Human HLA-A*0201 NY-ESO-1 complex Protein (C-10His)
Sizes: 10μg, 50μg
Catalogue Numbers: PKSH034036-10, PKSH034036-50
Citations, Manuals and MSDS Available upon request.
Abbreviation: HLA-A*0201 NY-ESO-1 complex
Target Symptom: MHC; MY-ESO-1; HLA-A*0201 NY-ESO-1 complex Protein
Research Area: Microbiology; immunology; Cardiovascular; Cancer
Target Species: Human
Expression Host: HEK293 Cells
Fusion Tag: C-10His
UNIProt ID: P61769&P01892
Accession: P61769&P01892
Background: NY-ESO-1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy. Optimally assembled peptide-HLA-B2M trimer translocates to the surface of antigen-presenting cells, where it interacts with TCR and CD8 coreceptor on the surface of T cells.
Sequence: SLLMWITQC&Ile21-Met119&Gly25-Ile308(Ala269Val)
Purity: > 90 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 49.1 kDa
Observed MW: 55-60 kDa
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Research Use Only